MORIANA INNOVATIONS

Innovating Orthopaedics Through Intelligent Design

Johannesburg-based medical technology company. Bridging clinical insight with advanced engineering. Delivering next-generation orthopaedic solutions.

Company Overview

Who We Are

Moriana Innovations (Pty) Ltd is a Johannesburg-based medical technology and innovation holding company focused on the development, commercialization, and strategic partnering of next-generation orthopaedic devices and digital health technologies.

Founded and led by an experienced specialist arthroplasty surgeon, Moriana Innovations bridges deep clinical insight with advanced engineering to deliver solutions that improve patient outcomes and clinician efficiency.

Vision

Our vision is to become a globally relevant orthopaedic innovation platform originating from Africa.

Mission

Our mission is to design intelligent, clinically driven technologies that simplify orthopaedic practice, enable earlier diagnosis of complications, and improve long-term outcomes for patients undergoing joint replacement surgery.

Core Focus Areas

Strategic Priorities 2025–2028

Smart Sensor Technology

Development of smart sensor-enabled orthopaedic implants and external monitoring solutions for enhanced patient care.

AI-Supported Diagnostics

AI-supported and data-driven diagnostic platforms for post-operative care and early complication detection.

Innovation Translation

Translation of surgeon-led innovation into protected, scalable intellectual property for global impact.

Research & Development Strategy

Moriana Innovations operates a capital-efficient R&D model.

Core innovation, concept development, and clinical validation are led internally, while specialist engineering, prototyping, and software development are executed through partnerships with leading South African technology firms.

This approach enables rapid iteration, tight clinical feedback loops, and controlled development costs.

Portfolio Companies & Strategic Investments

Building the future of orthopaedic care through strategic partnerships

Strategic Equity Stake

ConnectedKnee

www.connectedknee.com

Digital Health Platform for Orthopaedic Monitoring

Moriana Innovations holds a strategic equity stake in ConnectedKnee, a digital health company developing IMU-based diagnostic and monitoring technology for orthopaedic applications.

2025–2026 Milestones
  • Completion of preclinical validation and animal studies
  • Refinement of sensor algorithms for activity recognition and implant performance monitoring
  • Regulatory pathway planning (SAHPRA / FDA strategy)

ConnectedKnee is positioned as a foundational digital platform enabling objective post-operative assessment, early detection of implant-related complications, and data-driven follow-up care.

Core Technologies
  • IMU Sensor Technology: Advanced inertial measurement units for precise motion tracking
  • Real-Time Monitoring: Continuous implant performance and patient activity assessment
  • Clinical Integration: Seamless data flow to healthcare providers for informed decision-making
Strategic Shareholding

Theravane

www.theravane.co

Therapeutic & Rehabilitation Technologies

Through its shareholding in Theravane, Moriana Innovations has expanded into complementary therapeutic and rehabilitation-adjacent technologies that align with its broader orthopaedic ecosystem strategy.

Therapeutic Innovation
  • Advanced therapeutic modalities for musculoskeletal conditions
  • Integration with orthopaedic care pathways
  • Evidence-based rehabilitation protocols for optimal outcomes

Theravane's technologies complement Moriana's portfolio by addressing the full spectrum of orthopaedic care, from surgical intervention through rehabilitation and long-term wellness.

Ecosystem Integration
  • Holistic Care Approach: Bridging surgical excellence with post-operative therapeutic support
  • Patient-Centered Solutions: Technologies designed to enhance quality of life and functional outcomes
  • Clinical Synergy: Aligning innovation across the orthopaedic care continuum

Intellectual Property Portfolio

Building a defensible innovation platform

Moriana Innovations has built a growing and defensible intellectual property portfolio, developed under the leadership of founder Dr. Lipalo Mokete. The IP strategy is focused on platform technologies with multiple downstream commercialization pathways, including licensing, joint ventures, and spin-out companies.

Next-Generation Knee Prosthesis Concepts

Advanced knee replacement designs representing breakthrough innovations in joint arthroplasty technology. These concepts address key clinical challenges in primary and revision knee replacement surgery, focusing on improved long-term outcomes and enhanced biomechanical performance. Developed through deep clinical insight from specialist practice.

Image courtesy of zimmerbiomet.eu

Novel Prosthetic Bearing and Articulation Designs

Innovative bearing and articulation technologies engineered for enhanced durability and superior biomechanical performance in orthopaedic implants. These designs address critical wear characteristics and articulation mechanics that directly impact implant longevity and patient function. The protected concepts represent platform technologies with applications across multiple joint replacement systems, positioned for downstream commercialization through strategic partnerships with established orthopaedic device manufacturers.

Image courtesy of spartan.com

Smart Orthopaedic Device Architectures and Sensor Integration Concepts

Comprehensive sensor integration and monitoring concepts enabling intelligent orthopaedic systems with real-time data collection capabilities. These architectures provide the foundation for objective post-operative assessment, early detection of implant-related complications, and data-driven clinical follow-up. The protected concepts align with the digital health direction of modern orthopaedics.

Founder & Executive Leadership

Dr. Lipalo Mokete

Dr. Lipalo Mokete

FRCS FCOrth(SA)
Founder & Managing Director

Specialist Arthroplasty Surgeon | Academic | Medical Technology Entrepreneur

Dr. Mokete is a fellowship-trained joint replacement surgeon with extensive experience in primary and revision hip and knee arthroplasty.

He is widely recognized as a pioneer of robotic-assisted joint replacement surgery in South Africa and was the country's first certified robotic joint replacement surgeon.

His clinical practice, academic involvement, and entrepreneurial activity uniquely position him to identify unmet needs in orthopaedic care and translate them into commercially viable technologies.

Clinical & Academic Expertise
Primary and complex revision joint replacement surgery
Management of infected arthroplasty cases
Robotic-assisted surgery (Mako, CORI, ROSA platforms)
Surgical training, mentorship, and postgraduate teaching
Peer-reviewed publications and clinical research
Special interest in sensor technology and intelligent orthopaedic systems

Growth & Commercial Strategy

Moriana Innovations is positioned for growth through a combination of IP development, strategic partnerships, and selective capital raising.

Clinical Validation

Advancing portfolio companies through preclinical and early clinical validation

Regulatory Strategy

Strengthening regulatory and reimbursement strategies

Collaborations

Expanding international academic and industry collaborations

Commercialization

Preparing technologies for licensing or spin-out investment

The company is open to strategic investment, co-development partnerships, and industry collaborations aligned with its long-term vision.

Get In Touch

For partnership, investment, or collaboration enquiries, please contact us.

Moriana Innovations (Pty) Ltd

157 Bryanston Drive
Johannesburg, South Africa

Partnership Opportunities
  • Strategic Investment
  • Co-Development Partnerships
  • Industry Collaborations
  • Licensing Opportunities
"Innovating Today for Better Outcomes Tomorrow"

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